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ALDH3B2

ALDH Gene Record


Summary for ALDH3B2
Trivial Names & Synonyms
Database Accession ID's
Molecular Features
Polymorphisms
Substrates and Kinetic Values
Tissue Expression & Cellular Localization
Reference List

ALDH3B2

Summary for ALDH3B2:

ALDH3B2 is a mitochondrial homodimer. No functional data has been reported in the literature for ALDH3B2.

 
 

Trivial Names and Synonyms for ALDH3B2:

Acetaldehyde dehydrogenase 8,    Aldehyde dehydrogenase 8,    ALDH8
 
 

Database Accession ID's for ALDH3B2:

Species Gene-related Accession ID's Transcript-related Accession ID's Protein-related Accession ID's
Homo sapiens
(Human)
Institute Database Accession No.
NCBIEntrez Gene222
NCBIGenBankNC_000011
NCBIOMIM601917
NCBIUniGene87539
HUGOHGNC411
EBI, WTSIEnsembl - GeneViewENSG00000132746
Institute Database Accession No.
NCBIGenBankNM_001031615, NM_000695
Institute Database Accession No.
NCBIAceViewALDH3B2.aApr07, ALDH3B2.cApr07, ALDH3B2.bApr07
NCBIEntrez ProteinNP_001026786, NP_000686
EBI, WTSIEnsembl - ProtViewENSP00000255084
EBI, WTSIEnsembl - TransViewENST00000349015
EBI, SIB, PIRUniProtQ53Y98, P48448
 
Species Gene-related Accession ID's Transcript-related Accession ID's Protein-related Accession ID's
Mus musculus
(House mouse)
Institute Database Accession No.
NCBIEntrez Gene621603
NCBIGenBankNC_000085
NCBIUniGene266843
MCWRGD1308427
JLMGI2147613
Institute Database Accession No.
NCBIGenBankXM_129134
EBI, WTSIEnsembl - TransViewENSMUST00000100032
Institute Database Accession No.
NCBIEntrez ProteinXP_129134
EBI, WTSIEnsembl - TransViewENSMUSP00000097609
 
Species Gene-related Accession ID's Transcript-related Accession ID's Protein-related Accession ID's
Rattus norvegicus
(Norway rat)
Institute Database Accession No.
NCBIEntrez Gene361691
NCBIGenBankNC_005100
Institute Database Accession No.
NCBIGenBankXM_001068348
Institute Database Accession No.
NCBIGenBankXP_001068348
 
 
 

Molecular Features for ALDH3B2:

Species  
Homo sapiens
(Human)
Chromosome Locus : 11 q 13 (- strand)
 

 
ALDH3B2_v1     (Alternative Splice Variant 1) Number of Exons for ALDH3B2_v1 :   10 Click Here for Homo sapiens Transcript Sequences for Alternative Splice Variant 1
Click Here for Homo sapiens Peptide Sequences for Alternative Splice Variant 1
Transcript Length
(b.p.'s)
Peptide Translation Length
(a.a.'s)
M.W.
(Da)
Isoelectric Point Comments
ENST00000349015 2649 ENST00000349015 385 42635 5.86 Click Here for Graphical and Tabular Details

NM_000695 2660 NP_000686 385 42624 5.70 Click Here for Graphical and Tabular Details

SNP's : 3 single nucleotide polymorphism(s) identified

ALDH3B2.aApr07 2791 ALDH3B2.aApr07 385 42635 5.65 Click Here for Graphical and Tabular Details

 
 
ALDH3B2_v2     (Alternative Splice Variant 2) Number of Exons for ALDH3B2_v2 :   10 Click Here for Homo sapiens Transcript Sequences for Alternative Splice Variant 2
Click Here for Homo sapiens Peptide Sequences for Alternative Splice Variant 2
Transcript Length
(b.p.'s)
Peptide Translation Length
(a.a.'s)
M.W.
(Da)
Isoelectric Point Comments
NM_001031615 2504 NP_001026786 385 42624 5.70 Click Here for Graphical and Tabular Details

SNP's : 3 single nucleotide polymorphism(s) identified

ALDH3B2.bApr07 2511 ALDH3B2.bApr07 385 42635 5.65 Click Here for Graphical and Tabular Details

 
 
ALDH3B2_v3     (Alternative Splice Variant 3) Number of Exons for ALDH3B2_v3 :   9 Click Here for Homo sapiens Transcript Sequences for Alternative Splice Variant 3
Click Here for Homo sapiens Peptide Sequences for Alternative Splice Variant 3
Transcript Length
(b.p.'s)
Peptide Translation Length
(a.a.'s)
M.W.
(Da)
Isoelectric Point Comments
ALDH3B2.cApr07 1463 ALDH3B2.cApr07 357 39349 5.74 Click Here for Graphical and Tabular Details

 
Species  
Mus musculus
(House mouse)
Chromosome Locus : 19 A (+ strand)
 

 
ALDH3B2_v1     (Alternative Splice Variant 1) Number of Exons for ALDH3B2_v1 :   10 Click Here for Mus musculus Transcript Sequences for Alternative Splice Variant 1
Click Here for Mus musculus Peptide Sequences for Alternative Splice Variant 1
Transcript Length
(b.p.'s)
Peptide Translation Length
(a.a.'s)
M.W.
(Da)
Isoelectric Point Comments
XM_129134 2161 XP_129134 479 52983 5.78 Click Here for Graphical and Tabular Details

Transcript : Predicted

ENSMUST00000100032 2143 ENSMUSP00000097609 479 52983 5.78 Click Here for Graphical and Tabular Details

Transcript : The peptide translation results in a 479 a.a. product. However the Ensembl ProtView only shows a 211 a.a. peptide product for Accession ID ENSMUSP00000097609. That translation is incorrect.

Peptide : The Ensembl ProtView shows a 211 amino acid product for this transcript. This is an incorrect translation.

 
Species  
Rattus norvegicus
(Norway rat)
Chromosome Locus : 1 q 42 (+ strand)
 

 
ALDH3B2_v1     (Alternative Splice Variant 1) Number of Exons for ALDH3B2_v1 :   9 Click Here for Rattus norvegicus Transcript Sequences for Alternative Splice Variant 1
Click Here for Rattus norvegicus Peptide Sequences for Alternative Splice Variant 1
Transcript Length
(b.p.'s)
Peptide Translation Length
(a.a.'s)
M.W.
(Da)
Isoelectric Point Comments
XM_001068348 1410 XP_001068348 469 51674 5.67 Click Here for Graphical and Tabular Details

Transcript : Very interesting: Exons 2, 3, 4, 5, and 6 are duplicated 47000 bases upstream to this gene. Either a sequencing error in the genomic assembly or another piece of evidence for viral reverse transcriptase and gene duplication.

SNP's : 6 single nucleotide polymorphism(s) identified

 
 
 

Polymorphisms for ALDH3B2:

Currently Under Development
 
 

Substrates, Inhibitors and Enzyme Kinetics for ALDH3B2:

 
 

Tissue Expression & Cellular Localization for ALDH3B2:

Currently Under Development
 
 

Reference List for ALDH3B2:

ALDH3B2 Year Authors Title Journal Pubmed ID
1997 Hsu, Chang, Yoshida
Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison. Gene 9161417
 
1996 Hsu, Chang
Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family. Gene 8890755
 
 
 

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